What is Nitric Oxide? What comes to mind when you think about nitrates and nitrites? Perhaps meat preservatives. However, throughout the last dozens of years, the importance of these two molecules have become profound through their connection with nitric oxide (NO). Nitrates and nitrites are converted into NO through the nirate-nitrite-NO pathway that starts from
I would consider myself to be environmentally friendly – I use a reusable coffee cup, avoid plastic straws and carpool to work. However, until recently, I had never contemplated applying these principles of “Reduce, Reuse, Recycle” to my work in the Breast Clinic. Therapeutic monoclonal antibodies (mAbs) targeting specific antigens or receptors expressed on the
A recent study, now available on the preprint server bioRxiv from a team of researchers at the University of California San Francisco, features an innovative approach to stopping the spread of SARS-CoV-2, the virus behind the COVID-19 pandemic. The team has developed a synthetic aerosol nasal spray – which they termed “AeroNabs” – that works
Scientists at The Pirbright Institute, working closely with Inovio Pharmaceuticals, have proven that pigs can be used to determine whether influenza antibody therapies are effective. The team’s new research, recently published in the Journal of Immunology, found that a human antibody (2-12C) can neutralize the H1N1 2009 flu pandemic virus in pigs, which provides protection against
Researchers at the Korea Brain Research Institute (KBRI) discovered elevated levels of ACE2 during SARS-CoV-2 entry receptor gene expression in elderly patients with Alzheimer’s Disease (AD). The novel coronavirus (COVID-19), with its spread worldwide is reportedly hitting the elderly population most aggressively. Data has also shown that older people who have chronic comorbidities such as
A research study set to be published in the Journal of Experimental Medicine by a team at the Max Delbrück Center for Molecular Medicine (MDC) has identified a protein called Pdap1 that supports B cells from stress-induced cell death while encouraging antibody gene diversification. B Cells’ Role in the Immune System The body’s defense system
Physicians have always prescribed the standard treatment course of antibiotics for bacterial infections based on medical tradition. Now that antibiotic resistance has become a serious global health problem, researchers at the University of Geneva tested whether a shorter treatment, that is less likely to select for resistance, would have the same effect as the standard
At this critical time when the world is living through a global pandemic, research labs around the world are jumping to action to fight against the coronavirus. SARS-CoV-2 research is being conducted and clinical trials have started at an unparalleled rate. At Kerafast, we have quickly adapted to support the providers and research reagents that
Researchers at the University of California – Riverside examined the effect of the immune receptor Toll-like Receptor 4, or TLR4, on how memory functions in both the normal and injured brain. The results in this study published in Brain, Behavior, and Immunity shows the potential of treatments for limiting memory loss after brain injury. What is
A team of researchers at Brown University have uncovered a new target for fighting malaria, a mosquito-transmitted disease that kills almost a half-million people per year. In the study, they screened blood samples from children who already had a natural immune resistance to malaria in order to identify a malaria protein, known as PfGARP. The