Hydrodabcyl: a superior hydrophilic alternative to the dark fluorescence quencher dabcyl

Dark fluorescence quenchers are non-fluorescent dyes that can modulate the fluorescence signal of an appropriate fluorophore donor in a distance-dependent manner. Dark quenchers are often used in dual-label probes, which combine a reporter dye with a quencher moiety. Typically, these probes may exist in two conformations differing in their fluorescence properties: a ‘closed’ form in 

Continue Reading…

Research Reagent Appreciation Contest

Have you created or contributed to the development of a new research reagent? At Kerafast, our mission is to advance scientific research by facilitating access to unique reagents developed in academic laboratories around the world. This quarter, we invite you to share your experience in developing a new research reagent to be featured in our 

Continue Reading…

Cells Ability to Adapt to Hostile Environments in Critically Ill Patients

Researchers at the University of Plymouth collaborated with the University of College London and the Universities of Cambridge and Southampton to demonstrate that cells can adapt to conditions in critically ill patients by producing energy more efficiently than in healthy patients. Their research was published in Redox Biology. Oxygen and the Electron Transport Chain Within 

Continue Reading…

Generation of the First Pig Influenza Antibodies

The Pirbright Institute recently developed the first-ever pig antibodies against influenza. The study published in PLOS Pathogens proves successful protection against flu infections, validating that the new antibodies can be used for model studies of human antibody therapeutics and vaccines. The Pirbright team collaborated with the University of Oxford, The Francis Crick Institute and The 

Continue Reading…

Rapid Low-Cost Method to Measure COVID-19 Immunity

A research team led by Igor Stagljar at University of Toronto has been working to develop a new method of measuring the level of immunity to coronavirus in individuals who have recovered from COVID-19. Through their research, they have created a pinprick test that quickly and accurately measures the concentration of coronavirus antibodies in blood. 

Continue Reading…