Development of Photocleavable Alpha-Factor for Yeast

Development of Photocleavable Alpha-Factor for Yeast

Laurie L. Parker, PhD, Purdue University — Published: March 20, 2013 Diagram of Photocleavable Alpha-Factor for Yeast.This photocleavable alpha-factor analog incorporates a UV-cleavable linker into the backbone, which enables photolysis of the peptide upon exposure to UV light. This mimics Bar1 protease cleavage and cell cycle release. As a synthetic chemist moving into a new 

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