A new immunotherapy target for colorectal cancer

An international research team, led by scientists from Yale University, has identified a new immunotherapy target for treating colorectal cancer, developing an antibody that successfully reduces tumor formation in animal models. Though the antibody still needs to be tested in humans, it could eventually be used as a new immunotherapy inhibitor to treat colorectal and 

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X-ray laser puts Alzheimer’s proteins in new light

An international team of scientists has developed a new experimental technique that uses X-ray lasers to better analyze the structure of amyloids, large filamentous biomolecules implicated in neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Their method, recently outlined in the journal Nature Communications, opens up the ability to examine individual amyloid fibrils, the constituents of 

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A better understanding of methane-digesting bacteria

A recent study has revealed new information about the inner workings of methanotrophs, bacteria that metabolize methane for their source of energy. This process requires copper, and Northwestern University researchers have pinpointed two new proteins that help methanotrophic bacteria acquire copper from their surrounding environment. These findings have a variety of potential applications, both medical 

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A tale of the cell cycle gone wrong

The cell cycle is an intricate and coordinated process that is vital to sustain life. In higher eukaryotes, the cell cycle produces daughter cells identical to the mother cell to renew tissues in internal organs like the liver, skin and hair. The cell has checkpoints along the way to halt the cycle if something goes 

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New ways to combat antibiotic-resistant pneumonia

Like many other bacterial infections that affect humans, pneumonia has acquired a significant amount of antibiotic resistance, rendering traditional means of treatment ineffective. Researchers have been trying to find new ways to fight pneumonia and other infections for better treatment of patients. Recently, researchers led by Dr. Qingming Hou of Boston Children’s Hospital and Dr. 

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How red blood cells get their shape

Red blood cells must maintain a distinct dimpled shape as they travel through the body, returning to form even after pushing through narrow capillaries. Misshapen red blood cells are associated with disorders such as sickle cell anemia, and though red blood cells are well-studied, there are still unanswered questions about how healthy ones properly maintain 

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