Immature immune cells aid in spreading cancer

Ninety percent of cancer deaths are related to metastasis, making research to understand its causes and identify potential ways to prevent it very important. In a new Nature Communications study, scientists at the Georgia Cancer Center at Augusta University report that cancer can hijack a certain type of immature immune cell to help it spread. 

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How an antibody inhibits Zika virus infection

We recently wrote about a Nature study in which scientists identified a human monoclonal antibody able to protect pregnant mice and their developing fetuses from Zika virus infection. The research was led by Dr. James E. Crowe of Vanderbilt University, whose CD40L Expressing Feeder Cell Line, used to generate B cell cultures yielding human monoclonal 

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Antibodies 101

Antibodies are Y-shaped proteins produced naturally by the body’s immune system when it detects foreign substances. These proteins are commonly used in research to identify, locate and visualize intracellular and extracellular proteins. Antibodies are also being used for clinical applications, in particular as cancer therapeutics and in vaccine development. Here you’ll find a quick overview 

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New insights into ubiquitin regulation

Research from the University of Würzburg is providing new insights into ubiquitin regulation. In a recent study, published in the journal eLife, researchers determined the atomic structure of a ubiquitin ligase implicated in tumor formation, revealing a dimerization mechanism that may be exploited for developing new cancer therapies. The paper cited Kerafast’s LOBSTR E. coli 

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Treatment of burns with fish skin

Treatment of severe burns is a critical care issue, especially in developing countries. In the United States, donated human or pig skin is generally used to graft on the injured patient. However, some countries do not have access to the biobanks and animal models necessary for treatment of burn victims. In Brazil, doctors are testing 

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Kerafast volunteer day at Cradles to Crayons

A team of Kerafast employees spent one morning last week volunteering at a local Boston-based charity, Cradles to Crayons. The organization helps children 12 years and younger living in homeless or low-income situations by providing them with essentials such as clothing and school supplies. On Wednesday, we drove to Cradles to Crayons from our offices 

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