Engineered Monomeric Streptavidin 2 (Video)

Engineered Monomeric Streptavidin 2 (Video)

Sheldon Park, PhD, University at Buffalo — Published: August 27, 2013 Streptavidin is widely used in biotechnology and molecular research for detection, purification, crosslinking, and labeling of biotinylated targets. However, wild-type streptavidin is an obligate tetramer and can crosslink biotinylated targets. Target aggregation is a significant obstacle in some applications, including the labeling of biotinylated 

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