Kerafast

New insights into ubiquitin regulation

Research from the University of Würzburg is providing new insights into ubiquitin regulation. In a recent study, published in the journal eLife, researchers determined the atomic structure of a ubiquitin ligase implicated in tumor formation, revealing a dimerization mechanism that may be exploited for developing new cancer therapies. The paper cited Kerafast’s LOBSTR E. coli 

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Treatment of burns with fish skin

Treatment of severe burns is a critical care issue, especially in developing countries. In the United States, donated human or pig skin is generally used to graft on the injured patient. However, some countries do not have access to the biobanks and animal models necessary for treatment of burn victims. In Brazil, doctors are testing 

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Kerafast volunteer day at Cradles to Crayons

A team of Kerafast employees spent one morning last week volunteering at a local Boston-based charity, Cradles to Crayons. The organization helps children 12 years and younger living in homeless or low-income situations by providing them with essentials such as clothing and school supplies. On Wednesday, we drove to Cradles to Crayons from our offices 

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Meet Our New Product Specialist

Here at Kerafast, we recently welcomed a new member to our product management team. Molly Adams, a third-year bioengineering student at Northeastern University in Boston, joined the company in January as a Product Specialist. She’ll be with us as a full-time co-op student until the summer. As a Kerafast Product Specialist, Molly works on the 

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How the flu virus hijacks host cell RNA

In a recent study in Nature, scientists demonstrated how the influenza virus hijacks host cell RNA to proliferate within the human body. The research identified a specific mechanism common across all influenza strains, providing a new drug target with the potential to treat any influenza infection. In the paper, the investigators used the Influenza A, 

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Using evolutionary history to find genes linked to neurodevelopment disorders

Research from geneticists at Trinity College Dublin, recently published in Nature Communications, has identified a short list of genes implicated in many neurodevelopmental disorders and diseases, including autism, schizophrenia, ADHD and epilepsy. The study focused on regions of the genome called ‘copy number variants’ (CNVs). Common in humans, CNVs are areas of DNA that are 

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Researchers Create New Compounds to Treat Malaria

Malaria is a life-threatening disease caused by Plasmodium parasites. Anopheles mosquitos act as vectors for the disease, and Plasmodium parasites are transmitted through the bites of infected female mosquitos. Malaria transmission is most common in regions where Anopheles mosquitos are prevalent, such as in sub-Saharan Africa and South Asia. In 2015, 214 million worldwide cases 

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