Kerafast

How the flu virus hijacks host cell RNA

In a recent study in Nature, scientists demonstrated how the influenza virus hijacks host cell RNA to proliferate within the human body. The research identified a specific mechanism common across all influenza strains, providing a new drug target with the potential to treat any influenza infection. In the paper, the investigators used the Influenza A, 

Continue Reading…

Using evolutionary history to find genes linked to neurodevelopment disorders

Research from geneticists at Trinity College Dublin, recently published in Nature Communications, has identified a short list of genes implicated in many neurodevelopmental disorders and diseases, including autism, schizophrenia, ADHD and epilepsy. The study focused on regions of the genome called ‘copy number variants’ (CNVs). Common in humans, CNVs are areas of DNA that are 

Continue Reading…

Researchers Create New Compounds to Treat Malaria

Malaria is a life-threatening disease caused by Plasmodium parasites. Anopheles mosquitos act as vectors for the disease, and Plasmodium parasites are transmitted through the bites of infected female mosquitos. Malaria transmission is most common in regions where Anopheles mosquitos are prevalent, such as in sub-Saharan Africa and South Asia. In 2015, 214 million worldwide cases 

Continue Reading…

New details on antibiotic resistant bacteria

Bacteria gain resistance to antibiotics via mutation events in their genome. A recent study published in Nature Communications sheds new light on a gene that decreases mutation rates in Mycobacterium smegmatis, a model for Mycobacterium tuberculosis. M. tuberculosis is a highly infectious microbe that is the causative agent of tuberculosis (TB). According to the Centers 

Continue Reading…

Antibody protects pregnant mice & their fetuses from Zika virus infection

A team of scientists from Vanderbilt University Medical Center and Washington University School of Medicine in St. Louis have identified a human monoclonal antibody able to protect pregnant mice and their developing fetuses from Zika virus infection. The research, published in November in Nature, was led by a Kerafast providing investigator from Vanderbilt University, co-senior 

Continue Reading…

New insights toward retroviral evolution

Viruses are continually finding ways to infect their hosts and evade their defenses. Through the evolution of the human race, we have been continually fighting viruses. A recent study published in the journal Nature Communications demonstrates that, in fact, this fight may have been going on much longer than originally thought. Ancient retroviral origins The 

Continue Reading…

10 unique reagents that helped advance research in 2016

At Kerafast, our mission is to facilitate access to unique reagents developed by academic researchers. Together with our providing investigators, we get one-of-a-kind bioreagents into the hands of scientists worldwide who can use the materials to accelerate their own research. As we begin 2017, we took the opportunity to review how reagents in our catalog 

Continue Reading…

How killer T cells control Zika infection

Zika, a virus transmitted primarily by Aedes mosquitoes, became a significant global health concern last year. The threat emerged in Brazil and quickly spread to other parts of the world, causing microencephaly and other birth defects in babies born to infected mothers, as well as rare neurological conditions in adults. Although Zika has faded from 

Continue Reading…