Development of a Fluorescent Imaging Probe Specific for Neutrophils

Development of a Fluorescent Imaging Probe Specific for Neutrophils

Travis Riedel, PhD — Published: February, 28, 2013 This reagent is a Cyanine7-conjugated, PEG-modified hexapeptide that specifically binds the formyl peptide receptor (FPR) of neutrophils. After tail vein injection of the agent, sites of inflammation where neutrophils have been recruited and activated can be imaged in vivo by near-infrared (NIR) fluorescence. This Neutrophil-Specific, NIR Fluorescent 

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