A new research technique helps visualize a previously invisible process, showing how colon cancer cells grow and spread. Researchers at Duke Cancer Institute have used a modeling system in mice to observe how stem cell mutations arise in the colon. These mutations eventually take over and become malignant, leading to cancer. Their research was published
As 2019 comes to an end, we like to look back and see how the reagents in our catalog have contributed toward scientific advances this past year. Our company mission is to facilitate access to unique reagents developed by academic laboratories. Together with our providing investigators, we work to take reagents sitting in laboratory freezers
It is tradition at Kerafast during the holidays for the team to get together and give back to the Boston community. This year we have decided to collect donations for Cradles to Crayons, a non-profit organization that strives to provide every child with the essentials they need to feel safe, warm and valued. According to the organization,
Around 6,000 years ago, a contagious canine cancer began in Asia and has since spread around the world between dogs, likely during mating. The cancer was able to travel overseas mainly due to maritime activities. Rising from one original dog and spreading to new dogs around the world, today, canine transmissible venereal tumor (CTVT) is
A new research platform is using zebrafish to create new drug therapies to treat spinal cord injuries. The research team is led by Leonor Saúde at Instituto de Medicina Molecular in Lisbon, Portugal. In July 2019, their study was published in Scientific Reports, reporting proof for using zebrafish combined with drug repurposing to accelerate the
As of July 2019, researchers at the University of Guelph were the first to discover how the cannabis plant produces pain-relieving molecules that are extremely effective in reducing inflammation. Their complete findings were published in the journal Phytochemistry. This research opens the door for future cannabis studies and the production of natural pain relief treatments
New research from Cincinnati Children’s Hospital is helping scientists to understand a protein named Merlin, which plays an important role in the development of a condition known as neurofibromatosis 2 (NF2). A new study led by Robert Hennigan, PhD and Nancy Ratner, PhD and published in Science Signaling used a technique, known as proximity biotinylation,
Super-resolution microscopy has allowed scientists at the Stowers Institute for Medical Research to identify what causes interchromosomal linkages. Their findings cited our c-Myc lentivirus and were published in the Journal of Cell Biology. The composition of interchromosomal linkages Interchromosomal linkages were discovered by researchers in the 1960s while studying the organization of the human genome;
An international team of researchers has been able to demonstrate the impact of nanoparticles on human B lymphocytes, the immune cells responsible for antibody production. The results of their research, published in the journal ACS Nano, could lead to more effective vaccines and other therapeutics. Nanoparticles as Vaccine ‘Vehicles’ Because B lymphocytes are responsible for
Researchers at Boston Children’s Hospital and MIT have recently been able to show that mini-antibodies called nanobodies – previously discovered more than 20 years ago – may be able to resolve an issue in the cancer field: making chimeric antigen receptor (CAR) T-cell therapies functional in solid tumors. Their research was published in the journal