Researchers develop new vancomycin to combat antibiotic-resistant bacteria

The Centers for Disease Control and Prevention (CDC) report that more than 2 million people in the United States become infected with an antibiotic-resistant strain of bacteria resulting in at least 23,000 deaths annually. Antibiotic resistance is of growing concern with the increase in resistant bacterial strains and the emergence of multi-drug resistant bacteria. The 

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Understanding chromosome repair to combat cancer

New research from University of California, Santa Cruz reveals a repair mechanism that allows cells to rescue very damaged chromosomes during the cell division process.  The study was published this June in the Journal of Cell Biology. Cells use a variety of checkpoints and safeguards to maintain chromosome integrity during cell growth and division. If 

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A simpler, cheaper method for high-resolution microscopy

In a study published in Nature Methods this spring, a team of researchers developed a way to use standard light microscopes to obtain very high-resolution pictures of tissue samples. The new method, termed iterative expansion microscopy, enables imaging at a resolution of 25 nanometers. Because it doesn’t require any specialized equipment, the new technique is 

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Selecting a lentiviral vector

Lentiviral vectors can mediate the efficient delivery, integration and expression of transgenes or short hairpin RNAs (shRNAs) in dividing as well as non-dividing cell hosts, either in vitro or in several organs in vivo. Lentiviruses enable stable long-term gene expression and are permanently integrated into the host genome. They have become important research tools, useful 

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Community Spotlight: Lidia Kulemina, PhD, Kerafast Fellow at the University of Florida

The Kerafast fellowship program provides scientists with real-life experience in technology commercialization, helping them develop skills for careers on the business side of life science. Our fellows work onsite at select providing institutions to identify, characterize and eventually commercialize novel research tools created by other scientists at their institution. One such fellow is Dr. Lidia 

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How bacteria can limit the spread of Zika virus

Zika virus is spread through the bite of infected Aedus species mosquitoes. While generally not a major concern to healthy adults, infection with Zika virus poses a significant threat to pregnant women and their fetuses. Zika infection while pregnant can lead to serious birth defects such as microcephaly and congenital Zika syndrome. Given the mode 

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New insights into DNA repair

Research from Aarhus University in Denmark is providing new details about the structure of a DNA repair complex, information which could improve chemotherapy treatment of cancer. The new paper, published in The Journal of Biological Chemistry, cites Kerafast’s LOBSTR E. coli Expression Strain, developed by Dr. Thomas U. Schwartz at the Massachusetts Institute of Technology 

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