New details on antibiotic resistant bacteria

Bacteria gain resistance to antibiotics via mutation events in their genome. A recent study published in Nature Communications sheds new light on a gene that decreases mutation rates in Mycobacterium smegmatis, a model for Mycobacterium tuberculosis. M. tuberculosis is a highly infectious microbe that is the causative agent of tuberculosis (TB). According to the Centers 

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Antibody protects pregnant mice & their fetuses from Zika virus infection

A team of scientists from Vanderbilt University Medical Center and Washington University School of Medicine in St. Louis have identified a human monoclonal antibody able to protect pregnant mice and their developing fetuses from Zika virus infection. The research, published in November in Nature, was led by a Kerafast providing investigator from Vanderbilt University, co-senior 

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New insights toward retroviral evolution

Viruses are continually finding ways to infect their hosts and evade their defenses. Through the evolution of the human race, we have been continually fighting viruses. A recent study published in the journal Nature Communications demonstrates that, in fact, this fight may have been going on much longer than originally thought. Ancient retroviral origins The 

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10 unique reagents that helped advance research in 2016

At Kerafast, our mission is to facilitate access to unique reagents developed by academic researchers. Together with our providing investigators, we get one-of-a-kind bioreagents into the hands of scientists worldwide who can use the materials to accelerate their own research. As we begin 2017, we took the opportunity to review how reagents in our catalog 

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How killer T cells control Zika infection

Zika, a virus transmitted primarily by Aedes mosquitoes, became a significant global health concern last year. The threat emerged in Brazil and quickly spread to other parts of the world, causing microencephaly and other birth defects in babies born to infected mothers, as well as rare neurological conditions in adults. Although Zika has faded from 

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Scientists Identify TRAP1 as Key Driver of Prostate Cancer

About 1 in 7 men will be diagnosed with prostate cancer in their lifetimes, according to the American Cancer Society, making it the second-most common form of cancer in American men. Recently, a potentially promising new therapeutic target for the disease was identified by scientists from The Wistar Institute, one of Kerafast’s providing institutions. The 

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New markers to assess Huntington’s disease progression

Huntington’s disease is a debilitating, progressive disease that is eventually fatal. Affecting nerves of the brain, Huntington’s disease (HD) deteriorates an individual’s mental and physical capabilities over time. A recent study published in The Journal of Experimental Medicine by Stanford University researchers identified potential biomarkers to assess disease progression and analyze treatment effectiveness. Huntington’s disease 

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How the microbiota influences Crohn’s disease

Crohn’s disease (CD) is an inflammatory bowel disease that causes chronic inflammation of the gastrointestinal tract, most commonly in the small intestine. It is estimated that more than a half million people in the United States suffer from CD. The most common symptoms of Crohn’s disease include diarrhea, abdominal cramping and weight loss. The complications 

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