University of Tokyo researchers have shown different insulin concentrations activate different cell signaling pathways, findings that may lead to better treatments for diabetes. The researchers tracked the effects of insulin using a trans-omics approach, combining multiple databases and large-scale experiments, and published their results in the journal iScience. We were excited to see our puromycin
Atherosclerotic disease – the narrowing of arteries due to plaque buildup – is a leading cause of death worldwide. It causes 15 million lives to be lost each year around the world, with 610,000 deaths estimated in the United States alone. In a new study, researchers have pinpointed one more reason why some people are
Intestinal inflammation involves a complex interaction between intestinal epithelial cells, intestinal microbiota and immune cells. Many factors are known to be involved in the onset of intestinal inflammation; however, an inciting factor responsible for triggering inflammation has not been identified. The ability to identify an inciting factor has been hampered by the lack of animal-based
The parasite that causes malaria, Plasmodium sp., can reproduce both sexually and asexually. A new study in PLOS Pathogens found that the parasite ‘plans’ their offspring based on their surrounding conditions. When in a host, the parasite reproduces asexually in the blood, which results in disease to the host. In order to spread the infection
University of Southern California researchers have developed an injectable freeze-dried polio vaccine that can be kept at room temperature in powder form for four weeks and then rehydrated without losing efficacy in mice. Because the vaccine doesn’t need refrigeration, it could potentially be used throughout more remote parts of the world where polio still lurks,