An international research team, led by scientists from Yale University, has identified a new immunotherapy target for treating colorectal cancer, developing an antibody that successfully reduces tumor formation in animal models. Though the antibody still needs to be tested in humans, it could eventually be used as a new immunotherapy inhibitor to treat colorectal and
Cancer is the leading cause of disease-related death in dogs, impacting our canine companions at the same rate as it affects humans. In both people and dogs, the estimated lifetime risk for cancer is approximately one in three. In Dr. Jaime Modiano’s lab in the College of Veterinary Medicine at the University of Minnesota, researchers
The first cases of acquired immune deficiency syndrome (AIDS) in the United States were reported in June 1981. Since then, the global HIV/AIDS epidemic has continued to grow, and an estimated 36.7 million people were living with HIV infection in 2016. Despite decades of research and billions of dollars spent in funding research, neither a
When a bacterial toxin infects a host, barriers are often in place as a preventative to protect the host’s cells. As little as a single copy of a toxin can kill a cell, and in general, the target of the toxin is a low abundant component of the cell. New research recently published in Current
An international team of scientists has developed a new experimental technique that uses X-ray lasers to better analyze the structure of amyloids, large filamentous biomolecules implicated in neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Their method, recently outlined in the journal Nature Communications, opens up the ability to examine individual amyloid fibrils, the constituents of