Development of Photocleavable Alpha-Factor for Yeast
Laurie L. Parker, PhD, Purdue University — Published: March 20, 2013 Diagram of Photocleavable Alpha-Factor for Yeast.This photocleavable alpha-factor analog incorporates a UV-cleavable linker into the backbone, which enables photolysis of the peptide upon exposure to UV light. This mimics Bar1 protease cleavage and cell cycle release. As a synthetic chemist moving into a new