Research from the University of Würzburg is providing new insights into ubiquitin regulation. In a recent study, published in the journal eLife, researchers determined the atomic structure of a ubiquitin ligase implicated in tumor formation, revealing a dimerization mechanism that may be exploited for developing new cancer therapies. The paper cited Kerafast’s LOBSTR E. coli
The gastrointestinal (GI) tract is innervated by the enteric nervous system (ENS) located within the GI tract, as well as through connections to the central nervous system (CNS). The ENS and CNS act in concert to control the homeostatic functions of the GI tract, such as digestion, secretion and motility. The constant, bi-directional communication between
Treatment of severe burns is a critical care issue, especially in developing countries. In the United States, donated human or pig skin is generally used to graft on the injured patient. However, some countries do not have access to the biobanks and animal models necessary for treatment of burn victims. In Brazil, doctors are testing
An international team of researchers, led by Dr. Johanna Ivaska of the Turku Centre for Biotechnology, has found that breast cancer cell metastasis can be prevented by the SHANK protein. Previously, SHANK had only been studied in the central nervous system; it’s mainly known for its link to autism. The new study was published in