Kerafast

We’ve moved! Take a tour of our new office

The Kerafast team has now officially moved into our new office space! We’re still in the same building, located on the water in Boston’s Innovation District. We’re even on the same floor, so our address remains the same. However, we’ve excited to have upgraded to a larger space, complete with a bigger lab and shipping 

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Fighting infection with antibacterial drones

The prevalence of antibiotic-resistant bacteria is an ever-growing problem that poses a significant threat to global health. An increasing number of infectious diseases are becoming more difficult, and in some cases impossible, to treat. While new antibiotics are being developed, it is unlikely that they will be effective against the most dangerous antibiotic-resistant bacteria. To 

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Mapping the brain for targeted therapies

While the brain has been significantly studied and its various regions identified, a new study by researchers at the University of Southern California published in the journal Nature Neuroscience describes a detailed map of the hippocampus that holds promise for new treatments. The hippocampus The hippocampus is located at the base of the brain and 

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Potential cancer treatment found in alpaca’s immune system

An Institute for Research in Biomedicine (IRB Barcelona) and Vrije Universiteit Brussel (VUB) study describes camelid nanobodies with the capacity to block the activity of EGF (Epidermal Growth Factor), a protein that is abnormally regulated in cancer cells. Nanobody overview Nanobodies are an exciting area of research with the potential to help in the generation 

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Protection against Legionnaires’ disease and other lung infections

An international team of researchers has shown that MAIT cells, recently discovered immune cells whose exact function remains unclear, play a role in protecting against two strains of Legionella bacteria, which cause the lung infection Legionnaire’s disease. The results, published in Nature Communications, offer a potential new approach for protecting people against lung infections. We 

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Kerafast sponsors charity hockey tournament

Perhaps you have heard about the ice bucket challenge, a social media campaign from several summers ago. This challenge “dared” people to pour a bucket of ice water over their heads or give money to support ALS (amyotrophic lateral sclerosis), also known as Lou Gehrig’s Disease, and pass it on via social media. The inspiration 

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Neutralizing the Ebola virus with newly identified antibodies

A recent study in the journal Immunity describes the isolation and identification of two monoclonal antibodies that effectively protect against three different Ebola viruses. The research was led by Dr. James E. Crowe, Jr. of Vanderbilt University, whose B Cell Activating Feeder Cell Line, used to generate B cell cultures yielding human monoclonal antibodies, is 

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Spicy burn of chili peppers burns fat

Researchers from University of Wyoming have developed Metabocin, an anti-obesity drug derived from capsaicin, the part of a chili pepper that is responsible for its spicy burn. The capsaicin targets TRPV1 receptors to burn the energy in white fat cells rather than store it, and Metabocin has proven to effectively cause long-term weight loss in 

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Exploring alternative treatments for Clostridium difficile infection

Antibiotics have been effectively utilized for decades in the treatment against infectious agents. However, antibiotic use has been known to have detrimental effects, including the development of antibiotic-resistant bacteria and alterations to the microbiota. The microbiota is a community of bacteria that colonize the body and can influence metabolism, physiology, nutrition and immune function. An 

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