Kerafast

Super-resolution reveals the basis of interchromosomal linkages

Super-resolution microscopy has allowed scientists at the Stowers Institute for Medical Research to identify what causes interchromosomal linkages. Their findings cited our c-Myc lentivirus and  were published in the Journal of Cell Biology. The composition of interchromosomal linkages Interchromosomal linkages were discovered by researchers in the 1960s while studying the organization of the human genome; 

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Using Gold Nanoparticles for Vaccine Delivery

An international team of researchers has been able to demonstrate the impact of nanoparticles on human B lymphocytes, the immune cells responsible for antibody production. The results of their research, published in the journal ACS Nano, could lead to more effective vaccines and other therapeutics. Nanoparticles as Vaccine ‘Vehicles’ Because B lymphocytes are responsible for 

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Using Nanobodies to Improve CAR T-Cell Therapy

Researchers at Boston Children’s Hospital and MIT have recently been able to show that mini-antibodies called nanobodies – previously discovered more than 20 years ago – may be able to resolve an issue in the cancer field: making chimeric antigen receptor (CAR) T-cell therapies functional in solid tumors. Their research was published in the journal 

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A Future Focus for Parkinson’s Treatment

In a study published by the Journal of Biological Chemistry, scientists at UPenn School of Veterinary Medicine discovered that the enzyme cytochrome P450 2D6 (CYP2D6) plays a role in triggering Parkinson’s disease and represents a new focus for Parkinson’s treatment. Chemically induced Parkinson’s A few decades ago, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) was found to induce the onset 

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A New Target for Anti-Inflammation Therapeutics

Researchers from Washington State University recently discovered a critical step in the body’s inflammatory response that may aid in the development of anti-inflammatory treatments. Their findings, which were published in the journal Nature Communications, cited an integrin beta 3 antibody developed by researchers at the Blood Center of Wisconsin and now available via the Kerafast 

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Researchers discover new colon cancer therapeutic target

According to the U.S. Centers for Disease Control and Prevention, colon cancer is the third most common cancer and second leading cause of cancer-related death in the country. Now, food science researchers from the University of Massachusetts Amherst have published a new study in Cancer Research that shows how a set of enzymes can potentially 

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New paper uncovers the structure of CB2, the second human cannabinoid receptor

Findings from an international group of researchers might help in the development of drugs against inflammatory and neurodegenerative diseases. Their paper, published in Cell, describes the crystal structure of the human cannabinoid receptor CB2. Exploring the Endocannabinoid System CB1 and CB2, two cannabinoid receptors, belong to the endocannabinoid system. CB1 receptors are commonly found in 

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Combating T cell exhaustion in CAR T cancer therapy

Scientists from the La Jolla Institute of Immunology (LJI) have discovered a way to lessen the effects of T cell exhaustion and make CAR T cell therapies more effective, publishing their results in Nature. We were pleased to see our MC-38 cell line, derived from murine colon adenocarcinoma cells, utilized in the research. The MC-38 

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