Giving Back During the Holidays

This holiday season, the Kerafast team decided to give back to our local community by adopting an apartment at the Ronald McDonald House at Boston Harbor, where families of critically ill children can stay while their child receives care at a Boston-area treatment center. The organization provides lodging and support to these families, striving to 

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Studying insulin signaling using trans-omic analysis

University of Tokyo researchers have shown different insulin concentrations activate different cell signaling pathways, findings that may lead to better treatments for diabetes. The researchers tracked the effects of insulin using a trans-omics approach, combining multiple databases and large-scale experiments, and published their results in the journal iScience. We were excited to see our puromycin 

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New heart disease genetic risk factor discovered

Atherosclerotic disease – the narrowing of arteries due to plaque buildup – is a leading cause of death worldwide. It causes 15 million lives to be lost each year around the world, with 610,000 deaths estimated in the United States alone. In a new study, researchers have pinpointed one more reason why some people are 

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Using a gut-on-a-chip model to study intestinal inflammation

Intestinal inflammation involves a complex interaction between intestinal epithelial cells, intestinal microbiota and immune cells. Many factors are known to be involved in the onset of intestinal inflammation; however, an inciting factor responsible for triggering inflammation has not been identified. The ability to identify an inciting factor has been hampered by the lack of animal-based 

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Freeze-dried polio vaccine could end the disease

University of Southern California researchers have developed an injectable freeze-dried polio vaccine that can be kept at room temperature in powder form for four weeks and then rehydrated without losing efficacy in mice. Because the vaccine doesn’t need refrigeration, it could potentially be used throughout more remote parts of the world where polio still lurks, 

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