The Role of Chromatin and DNA Damage in Neurodegenerative Disorders

St. Jude Children’s Research Hospital has recently been conducting research on pediatric neurodegenerative disorders defined by mutations that affect DNA repair proteins and trigger progressive loss of Purkinje cells. The main two diseases they focused their research on were ataxia telangiectasia (A-T) and ataxia with oculomotor apraxia 1 (AOA1), which involve issues with motor skills 

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