An HIV drug may reduce the impact of age-related disorders

Research led by scientists at Brown University now shows that an HIV drug may be able to significantly reduce age-related inflammation and other signs of aging in mice. The collaborative findings — which also included work by researchers from New York University, the University of Rochester, Université de Montréal, the University of Virginia School of 

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Lysosomes receive calcium through close association with the ER and IP3 receptors

Free calcium in the cytosol is critical for regulating cellular processes in response to intracellular and extracellular stimuli. Calcium signaling involves the opening of calcium channels within the plasma membrane or membranes of intracellular organelles, most notably the endoplasmic reticulum (ER). Extracellular stimuli lead to the release of calcium from the ER in response to 

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10 unique reagents that helped advance research in 2018

At Kerafast, it’s become an annual tradition at the start of each year to look back at how the reagents in our catalog have helped contribute to scientific progress. Our company mission is to facilitate access to the unique reagents developed by academic laboratories. Together with our providing investigators, we get lab-made reagents out of 

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Cell-Based Meat Gears Up for Public Market

International and bay-area startups are in a R&D race to bring cell-based meat (also known as clean meat, cultured meat and in vitro meat) to market. At its core, the concept of cell-based meat is fairly straightforward: myoblast stem cells are cultured and directed to form myocytes, which may then be compacted to form ground 

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Giving Back During the Holidays

This holiday season, the Kerafast team decided to give back to our local community by adopting an apartment at the Ronald McDonald House at Boston Harbor, where families of critically ill children can stay while their child receives care at a Boston-area treatment center. The organization provides lodging and support to these families, striving to 

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Studying insulin signaling using trans-omic analysis

University of Tokyo researchers have shown different insulin concentrations activate different cell signaling pathways, findings that may lead to better treatments for diabetes. The researchers tracked the effects of insulin using a trans-omics approach, combining multiple databases and large-scale experiments, and published their results in the journal iScience. We were excited to see our puromycin 

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New heart disease genetic risk factor discovered

Atherosclerotic disease – the narrowing of arteries due to plaque buildup – is a leading cause of death worldwide. It causes 15 million lives to be lost each year around the world, with 610,000 deaths estimated in the United States alone. In a new study, researchers have pinpointed one more reason why some people are 

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