Photoreactive HDAC Inhibitors: A New Way to Form A Stable Relationship with HDACs
Marcos Salazar March 10, 2014 The deregulation of histone deacetylases (HDACs) has the potential to instigate various cancers and neurodegenerative diseases. Dr. Pavel A. Petukhov has cleverly designed HDAC inhibitors containing a photoreactive element that selective form a stable bond with HDACs and inhibit their detrimental effects. Histone deacetylases (HDACs) have managed to maintain a